Low-cost droplet microfluidic screening platforms
Droplet microfluidics enables the screening of biological and chemical systems at unprecedented throughput, yet wide adoption has been limited by bespoke and expensive design and fabrication processes. At the CIDAR Lab, we have built out a series of rapid prototyping pipelines to build sophisticated droplet microfluidic components at a fraction of a cost.
Using these base components, we aim to build out a full library of reconfigurable and modular droplet microfluidic devices with highly predictable outcomes (covering the parameter changes shown below). With this, we aim to eliminate the barriers to adoption for microfluidic platforms by life scientists, and accelerate experimentation in synthetic biology by orders of magnitude.
McIntyre, David, Ali Lashkaripour, and Douglas Densmore. "Rapid and inexpensive microfluidic electrode integration with conductive ink." Lab on a Chip 20, no. 20 (2020): 3690-3695. LINK
Lashkaripour, Ali, Christopher Rodriguez, Luis Ortiz, and Douglas Densmore. "Performance tuning of microfluidic flow-focusing droplet generators." Lab on a Chip 19, no. 6 (2019): 1041-1053. LINK
Lashkaripour, Ali, Ryan Silva, and Douglas Densmore. "Desktop micromilled microfluidics." Microfluidics and Nanofluidics 22, no. 3 (2018): 1-13 LINK